Asplenia


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Coding system
CTV3 (Read V3) with TPP extensions
Organisation
OpenSAFELY
Codelist ID
opensafely/asplenia
Version
2020-06-02
Versions
  • 2020-06-02

Description

Codes indicating diagnosis of asplenia or dysplenia (acquired or congenital)

Methodology

This codelist was derived by the following method:

  • Read 2 Codelist provided by LSHTM. See references for paper.
  • Codes from Quality Outcome Framework (QOF) were examined and relevant spleen codes taken
  • Codes from SNOMED were taken by searching for relevant spleen terms

These 3 lists were mapped into CTV3 by TPP to create one list. This list was examined by 2 people and the following logic applied (see github issue for more detail):

  • Splenomegaly or splenic cysts excluded as no evidence of reduced function
  • Congenital syphilis which appears in the list due to one code with congenital syphilitic splenomegaly was excluded. Congenital syphilitic splenomegaly was included however.
  • All unspecified injuries to spleen for example trauma were excluded except where removal of spleen was specified.
  • Removal of accessory spleen was excluded

References

Signed off by

  • Caroline Morton, (April 14, 2020)
  • Alex Walker, (April 14, 2020)
  • Henry Drysdale, (June 2, 2020)

This definition has been computed by taking the manually created full codelist and converting it to a list of rules that define the codelist.

  • (Absent spleen) or (asplenia) (PK01.)
  • Atrophy of spleen (D4154)
  • Avulsion of spleen (XA07k)
  • Congenital absence of spleen (XE1Mi)
  • Congenital syphilitic splenomegaly (XM1OF)
  • Embolisation of spleen (78421)
  • Embolism and thrombosis of the splenic artery (G74y6)
  • H/O splenectomy (14N7.)
  • Hereditary splenic hypoplasia (Xa9D7)
  • Hypoplasia of spleen (PK06.)
  • Hyposplenism (Xa0hO)
  • Infarction of spleen (D4157)
  • Plasmodium vivax malaria with rupture of spleen (A8410)
  • Post-splenectomy leucocytosis (X20Fp)
  • Spleen absent (Xa7Ya) and all descendants
  • Splenectomy (X20BK) and all descendants except:
    • Excision of accessory spleen (78402)
  • Splenic fibrosis (D4156)
  • Splenic vein thrombosis (X205i)
CTV3ID CTV3PreferredTermDesc CTV3Source
14N7. H/O splenectomy CTV3Map_Code_And_Term
7840. Total splenectomy CTV3Map_Code_And_Term
7840. Total splenectomy CTV3Map_Code_Only
7840. Total splenectomy QOF
78400 Total splenectomy and reimplantation of fragments CTV3Map_Code_And_Term
78401 Total splenectomy High_Level_SNOMED
78403 Splenectomy NEC CTV3Map_Code_And_Term
78403 Splenectomy NEC QOF
7840y Other specified total excision of spleen CTV3Map_Code_And_Term
7840y Other specified total excision of spleen QOF
7840z Total excision of spleen NOS CTV3Map_Code_And_Term
7840z Total excision of spleen NOS QOF
7841. Other excision of spleen CTV3Map_Code_And_Term
7841. Other excision of spleen QOF
78410 Partial splenectomy CTV3Map_Code_And_Term
7841y Other specified other excision of spleen CTV3Map_Code_And_Term
7841y Other specified other excision of spleen QOF
7841z Other excision of spleen NOS CTV3Map_Code_And_Term
7841z Other excision of spleen NOS QOF
78421 Embolisation of spleen CTV3Map_Code_And_Term
A8410 Plasmodium vivax malaria with rupture of spleen QOF
D4154 Atrophy of spleen CTV3Map_Code_And_Term
D4154 Atrophy of spleen QOF
D4156 Splenic fibrosis CTV3Map_Code_And_Term
D4156 Splenic fibrosis QOF
D4157 Infarction of spleen CTV3Map_Code_And_Term
D4157 Infarction of spleen QOF
G74y6 Embolism and thrombosis of the splenic artery CTV3Map_Code_And_Term
PK01. (Absent spleen) or (asplenia) High_Level_SNOMED
PK06. Hypoplasia of spleen CTV3Map_Code_And_Term
PK06. Hypoplasia of spleen QOF
Ua1JD Subtotal splenectomy CTV3_Children
X205i Splenic vein thrombosis QOF
X20BK Splenectomy QOF
X20Fp Post-splenectomy leucocytosis QOF
XA07k Avulsion of spleen QOF
XE1Mi Congenital absence of spleen CTV3Map_Code_And_Term
XE1Mi Congenital absence of spleen CTV3Map_Code_Only
XE1Mi Congenital absence of spleen QOF
XM1OF Congenital syphilitic splenomegaly CTV3Map_Code_And_Term
Xa0hO Hyposplenism CTV3Map_Code_And_Term
Xa0hO Hyposplenism QOF
Xa7Ya Spleen absent CTV3Map_Code_And_Term
Xa7Ya Spleen absent CTV3Map_Code_Only
Xa7Ya Spleen absent QOF
Xa9D7 Hereditary splenic hypoplasia QOF
XaEXw Laparoscopic total splenectomy CTV3Map_Code_And_Term
XaEXw Laparoscopic total splenectomy QOF
XaZvR Acquired absence of spleen CTV3_Children
XaZvR Acquired absence of spleen QOF

Codes not in the full codelist are in faint grey.